Levetiracetam Side Effects in Adults: 12 Common Types and Warnings

Levetiracetam is a commonly prescribed anti-epileptic drug used to treat seizures in adults. While generally well-tolerated, it can cause a range of side effects, some of which can be significant.

Common Side Effects of Levetiracetam in Adults

1. Somnolence (Drowsiness): Up to 56% of adults experience drowsiness with levetiracetam use.
2. Headache: Occurs in up to 20% of adults.
3. Asthenia (Weakness): Fatigue and weakness are reported by up to 18% of users.
4. Dizziness: Affects approximately 13% of adults taking levetiracetam.
5. Nausea: Reported by up to 11% of adults.
6. Ataxia (Lack of Coordination): Occurs in approximately 7% of adults.
7. Vomiting: Experienced by up to 5% of adults using levetiracetam.
8. Confusion: Observed in up to 4% of adults.
9. Depression: Approximately 2% of adults develop depression during levetiracetam treatment.
10. Psychotic Disorders: In severe cases, levetiracetam can trigger hallucinations or delusions.
11. Aggression: Irritability and aggression are reported by up to 2% of adults.
12. Weight Gain: Long-term levetiracetam use has been associated with weight gain in some adults.

Warnings and Precautions

While levetiracetam is generally safe and effective for most adults, there are several important warnings and precautions to consider:

• Suicidal Ideation: Levetiracetam has been linked to increased risk of suicidal thoughts or behaviors in children and adolescents. However, this risk is less clear in adults.
• Hepatic Impairment: Levetiracetam should be used with caution in adults with liver problems.
• Renal Impairment: Dosage adjustments may be necessary for adults with kidney disease.
• Drug Interactions: Levetiracetam can interact with other medications, such as antipsychotics and antidepressants.
• Pregnancy and Breastfeeding: Use of levetiracetam during pregnancy or breastfeeding should be discussed with a healthcare professional.

How to Step-by-Step Approach

1. Discuss with a Healthcare Professional: Before taking levetiracetam, discuss potential side effects and benefits with a doctor.
2. Start at a Low Dose: Begin with a low dose of levetiracetam and gradually increase as needed.
3. Monitor for Side Effects: Pay attention to how your body responds to levetiracetam and report any concerns to a healthcare professional.
4. Avoid Activities That Require Alertness: If you experience drowsiness or dizziness, avoid driving or operating heavy machinery.
5. Inform Other Healthcare Providers: Let other healthcare professionals know you are taking levetiracetam, as it may affect test results.

Common Mistakes to Avoid

• Skipping Doses: Do not skip doses of levetiracetam without consulting a healthcare professional.
• Taking Too Much Medication: Do not exceed the prescribed dosage of levetiracetam.
• Stopping Abruptly: Do not stop taking levetiracetam suddenly, as this can trigger seizures.
• Combining with Alcohol: Avoid consuming alcohol while taking levetiracetam, as it can worsen side effects.
• Using Expired Medication: Do not take levetiracetam that has expired.

Table 1: Prevalence of Side Effects in Adults

Table 2: Warnings and Precautions for Levetiracetam Use in Adults

Table 3: Tips for Managing Side Effects of Levetiracetam in Adults

Table 4: Common Mistakes to Avoid with Levetiracetam Use

Conclusion

Levetiracetam is a generally well-tolerated anti-epileptic drug, but it can cause a range of side effects in adults. By understanding the potential risks and benefits, and following the prescribed dosage and precautions, adults can safely and effectively use levetiracetam to manage their seizures.