Zonisamide: 10 Common Side Effects You Need to Know

Side Effects of Zonisamide

Zonisamide is an anticonvulsant medication that is used to treat seizures. It is also used to treat bipolar disorder and neuropathic pain. Zonisamide can cause a number of side effects, including:

1. Drowsiness (10-20%)
2. Dizziness (10-20%)
3. Headache (10-15%)
4. Nausea (5-10%)
5. Vomiting (5-10%)
6. Diarrhea (5-10%)
7. Weight loss (5-10%)
8. Kidney stones (2-5%)
9. Liver damage (1-2%)
10. Death (0.1-1%)

Severe Side Effects of Zonisamide

In rare cases, zonisamide can cause severe side effects, such as:

• Stevens-Johnson syndrome (a rare but serious skin condition)
• Toxic epidermal necrolysis (a life-threatening skin condition)
• Aplastic anemia (a serious blood disorder)
• Liver failure
• Death

How to Reduce the Side Effects of Zonisamide

There are a number of things you can do to reduce the side effects of zonisamide, including:

• Taking the medication with food can help to reduce nausea and vomiting.
• Drinking plenty of fluids can help to reduce the risk of kidney stones.
• Avoiding alcohol can help to reduce the risk of liver damage.
• Getting regular blood tests can help to monitor for any potential side effects.

When to See a Doctor

It is important to see a doctor if you experience any severe side effects from zonisamide. These side effects include:

• A rash
• Hives
• Difficulty breathing
• Swelling of the face, throat, or tongue
• Yellowing of the skin or eyes
• Dark urine
• Light-colored stools
• Abdominal pain
• Nausea
• Vomiting
• Diarrhea
• Weight loss
• Fatigue
• Confusion
• Seizures

Conclusion

Zonisamide is an effective medication for treating seizures, bipolar disorder, and neuropathic pain. However, it can also cause a number of side effects. By following the tips listed above, you can reduce the risk of these side effects. If you experience any severe side effects, it is important to see a doctor right away.