Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus characterized by an eosinophilic infiltrate. It is a relatively rare condition, with an estimated prevalence of 0.005% to 0.02% in the general population. However, it is becoming more common, and is now the most common cause of chronic esophagitis in children and adolescents.
The most common symptoms of EoE are:
EoE is diagnosed based on clinical symptoms and endoscopic findings. Endoscopy is a procedure in which a thin, flexible tube with a camera on the end is inserted into the esophagus. This allows the doctor to visualize the esophagus and look for signs of inflammation, such as:
A biopsy may also be performed to confirm the diagnosis. A biopsy involves removing a small sample of tissue from the esophagus and examining it under a microscope.
The treatment of EoE typically involves a combination of dietary changes and medications. Dietary changes that may be helpful include:
Medications that may be used to treat EoE include:
The prognosis for EoE is generally good. With treatment, most people with EoE are able to manage their symptoms and live a full and active life. However, some people with EoE may experience complications, such as:
There is no known way to prevent EoE. However, early diagnosis and treatment can help to reduce the risk of complications.
The ICD-10 codes for eosinophilic esophagitis are:
Symptom | Percentage of Patients |
---|---|
Dysphagia | 90-100% |
Food impaction | 50-75% |
Chest pain | 50-75% |
Heartburn | 30-50% |
Nausea and vomiting | 20-30% |
Abdominal pain | 10-20% |
Wheezing | 10-20% |
Cough | 10-20% |
Failure to thrive (in children) | 10-20% |
Finding | Percentage of Patients |
---|---|
Esophageal rings | 50-75% |
Linear furrowing | 50-75% |
White plaques | 30-50% |
Strictures | 10-20% |
Medication | Class |
---|---|
Proton pump inhibitors (PPIs) | Acid-suppressing agents |
Histamine-2 receptor antagonists (H2RAs) | Acid-suppressing agents |
Leukotriene inhibitors | Anti-inflammatory agents |
Topical steroids | Anti-inflammatory agents |
Biologics | Immunomodulatory agents |
Code | Description |
---|---|
K20.0 | Eosinophilic esophagitis, unspecified |
K20.1 | Allergic eosinophilic esophagitis |
K20.2 | Idiopathic eosinophilic esophagitis |
K20.3 | Eosinophilic esophagitis with eosinophilic gastrointestinal disease |
K20.8 | Other eosinophilic esophagitis |
K20.9 | Eosinophilic esophagitis, unspecified |
Eosinophilic esophagitis is a chronic inflammatory disease of the esophagus that is characterized by an eosinophilic infiltrate. It is a relatively rare condition, but it is becoming more common. The symptoms of
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