ICD-10 eosinophilic esophagitis (EoE) is a chronic inflammatory condition characterized by a buildup of eosinophils—a type of white blood cell—in the esophageal lining. This accumulation can lead to a range of symptoms, from mild discomfort to severe esophageal damage.
According to the American Gastroenterological Association, EoE affects approximately 1 in 2,000 people in the United States. Its prevalence has been increasing over the past few decades, with an estimated 15% of all esophageal biopsies now showing signs of EoE.
The symptoms of EoE can vary greatly depending on the individual. Common symptoms include:
Diagnosing EoE involves a thorough examination of the esophagus. This typically includes:
The primary goal of EoE treatment is to reduce eosinophil infiltration and inflammation in the esophagus. Treatment options include:
With proper management, the prognosis for EoE is generally favorable. Most patients can expect to experience significant improvement in their symptoms with treatment. However, EoE is a chronic condition that requires ongoing monitoring and management to prevent disease recurrence.
Untreated EoE can lead to serious complications, including:
Dietary management is an essential component of EoE treatment. The goal is to identify and avoid trigger foods that aggravate symptoms. Common trigger foods include:
Food Group | Common Trigger Foods |
---|---|
Dairy | Milk, cheese, yogurt |
Soy | Soy milk, soy beans, tofu |
Wheat | Bread, pasta, cereal |
Eggs | Whole eggs, egg whites, egg yolks |
Fish | Shellfish, tuna, salmon |
Nuts | Peanuts, tree nuts, nut butters |
Medications play a crucial role in controlling inflammation and reducing eosinophil counts in EoE. Common medications used include:
Medication Class | Drugs | Mechanism of Action |
---|---|---|
Proton Pump Inhibitors (PPIs) | Omeprazole, lansoprazole | Reduce stomach acid production |
Corticosteroids | Budesonide, fluticasone | Suppress inflammation |
Immunomodulators | Montelukast, cromolyn sodium | Block inflammatory pathways |
Endoscopic dilation is a procedure used to widen the esophageal lumen in cases of severe esophageal stricture. This involves inserting a balloon-tipped catheter into the esophagus and inflating it to stretch the narrowed area.
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