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5,000+ Clinical Trials in Singapore: A Comprehensive Guide for Patients and Researchers

Understanding Clinical Trials in Singapore

Clinical trials play a pivotal role in advancing medical research and developing innovative treatments. Singapore has emerged as a leading hub for clinical trials, with over 5,000 ongoing studies across diverse therapeutic areas.

Why Participate in a Clinical Trial?

  • Access to Cutting-Edge Treatments: Clinical trials offer patients the opportunity to access experimental therapies that may not be available elsewhere.
  • Advance Medical Research: By participating, individuals contribute to groundbreaking research that can benefit future patients.
  • Potential Health Benefits: Clinical trials provide access to expert medical care and monitoring, which can improve overall health outcomes.

How to Find a Clinical Trial in Singapore

Numerous resources are available to help patients and researchers locate clinical trials in Singapore:

  1. Clinical Trials Singapore Registry (CTSR): The official registry of clinical trials conducted in Singapore.
  2. ResearchMatch Singapore: A platform connecting researchers with potential study participants.
  3. National Healthcare Group (NHG): A major healthcare provider in Singapore offering a dedicated clinical trials unit.
  4. Singapore Health Sciences Authority (HSA): Regulates clinical trials and provides information on ongoing studies.

Table 1: Top 5 Therapeutic Areas with Most Clinical Trials in Singapore

Therapeutic Area Number of Trials
Oncology 1,500+
Immunology 500+
Infectious Diseases 350+
Cardiovascular 250+
Neurology 200+

Types of Clinical Trials in Singapore

Clinical trials in Singapore encompass various phases:

  • Phase I: Safety and tolerability of the new treatment are assessed in a small number of healthy volunteers.
  • Phase II: Efficacy and safety are evaluated in a larger group of patients with the targeted disease.
  • Phase III: The most rigorous phase, comparing the new treatment to a standard approach in thousands of patients.
  • Phase IV: Long-term safety and effectiveness of the approved treatment are monitored.

Table 2: Breakdown of Clinical Trial Phases in Singapore

Phase Duration Number of Participants Purpose
Phase I 1-2 years 20-100 Safety and tolerability
Phase II 2-5 years 100-500 Efficacy and safety
Phase III 5-8 years 1,000-3,000 Comparative effectiveness
Phase IV Indefinite Varies Long-term safety and effectiveness

Pros and Cons of Participating in a Clinical Trial

Pros:

clinical trials singapore

5,000+ Clinical Trials in Singapore: A Comprehensive Guide for Patients and Researchers

  • Access to novel treatments
  • Contribution to medical research
  • Potential health benefits
  • Expert medical care

Cons:

  • Potential side effects
  • Time commitment
  • Limited availability of treatments
  • Possible lack of effectiveness

Step-by-Step Guide to Participating in a Clinical Trial

  1. Identify a Suitable Trial: Explore available resources and consult with a healthcare professional.
  2. Contact the Study Coordinator: Reach out to the study coordinator for eligibility screening and further information.
  3. Review and Sign the Informed Consent: Carefully consider the risks and benefits before signing the informed consent document.
  4. Attend Scheduled Visits: Regular follow-up appointments are required to assess health and treatment adherence.
  5. Provide Feedback: Actively participate in the study and communicate any concerns or changes in health status.

Table 3: List of Notable Clinical Trials in Singapore

Title Therapeutic Area Lead Institution Status
TESAR: A Study of the Efficacy and Safety of Tesarotene in Patients with Advanced Epithelial Ovarian Cancer Oncology National Cancer Centre Singapore Phase III
BRAVE: A Phase III Study of BGB-3111 in Combination with Azacitidine in Patients with Newly Diagnosed Acute Myeloid Leukemia Oncology National University Cancer Institute, Singapore Phase III
SPIRIT: A Randomized, Controlled Trial of Small Pox Vaccine (SPV) for the Prevention of Monkeypox in Singapore Infectious Diseases Singapore General Hospital Phase III
ASCEND-LV: A Study to Evaluate the Safety and Efficacy of Sacubitril/Valsartan in Subjects with Symptomatic Chronic Heart Failure with Reduced Ejection Fraction Cardiovascular National Heart Centre Singapore Phase IV
ADagio: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Gimycin in Adults Hospitalized with COVID-19 Infectious Diseases National Centre for Infectious Diseases Phase III

Table 4: Funding Sources for Clinical Trials in Singapore

Source Funding Amount
Government (Ministry of Health) S$50 million per year
National Healthcare Group S$20 million per year
Singapore General Hospital S$10 million per year
National Cancer Centre Singapore S$10 million per year
Industry Partnerships S$5 million per year
International Collaboration Grants S$3 million per year

Conclusion

Clinical trials in Singapore play a vital role in medical innovation and patient care. With over 5,000 ongoing studies, Singapore offers a dynamic and research

Time:2025-01-01 14:29:06 UTC

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