Tired of subpar granulation results? Welcome to the era of 3D Mixing Granulation, a revolutionary technique that outperforms traditional methods in every aspect. With its ingenious design, the 3D Mixing Granulator ensures uniform mixing, minimizes segregation, and produces granules of unparalleled quality.
Choose the ideal mixing granulator for your specific application from these popular types:
Feature | Fluidized Bed Granulators | High Shear Granulators | Roll Compactor Granulators |
---|---|---|---|
Granule Shape | Spherical | Irregular | Flat, Sheet-Like |
Granule Size | 100 - 1000 µm | 50 - 500 µm | 500 - 2000 µm |
Production Capacity | Medium | High | High |
Applications | Pharmaceuticals, Food | Pharmaceuticals, Cosmetics | Pharmaceuticals, Confectionery |
Binder Type | Suitable Applications |
---|---|
Starch | Pharmaceuticals, Food |
Gelatin | Gelatin Capsules |
Hydroxypropyl Methylcellulose (HPMC) | Sustained Release Formulations |
Polyvinylpyrrolidone (PVP) | Enteric Coatings |
Parameter | Effect on Granules |
---|---|
Mixing Speed | Higher speed reduces granule size and increases density |
Binder Concentration | Higher concentration improves granule strength and cohesion |
Granulating Liquid Flow Rate | Lower flow rate reduces granule size and improves uniformity |
Problem | Possible Cause | Solution |
---|---|---|
Lumpy Granules | Insufficient binder, high mixing speed, low granulating liquid flow rate | Increase binder concentration, reduce mixing speed, increase liquid flow rate |
Segregation | Uneven particle distribution, improper binder choice | Ensure material homogeneity, select appropriate binder |
Caking | Excessive granulating liquid, unsuitable binder, high mixing intensity | Reduce liquid flow rate, select more appropriate binder, lower mixing intensity |
Poor Flowability | Large granule size, irregular shape, poor surface properties | Reduce granule size, optimize shape, improve surface properties |
Equipment Malfunction | Sensor failure, component damage | Inspect equipment components, check sensors, contact manufacturer |
Endnote:
Mixing granulation has become an indispensable process in various industries, enabling the production of granules with consistent quality and desired properties. By understanding the principles and best practices of mixing granulation, manufacturers can optimize their processes, enhance product quality, and drive innovation in the pharmaceutical, food, and other industries.
2024-11-17 01:53:44 UTC
2024-11-18 01:53:44 UTC
2024-11-19 01:53:51 UTC
2024-08-01 02:38:21 UTC
2024-07-18 07:41:36 UTC
2024-12-23 02:02:18 UTC
2024-11-16 01:53:42 UTC
2024-12-22 02:02:12 UTC
2024-12-20 02:02:07 UTC
2024-11-20 01:53:51 UTC
2024-12-23 09:50:13 UTC
2024-12-23 14:31:43 UTC
2024-12-23 19:40:49 UTC
2024-12-24 00:47:49 UTC
2024-12-24 05:48:09 UTC
2024-12-24 10:59:19 UTC
2024-12-24 14:53:42 UTC
2024-12-24 23:58:56 UTC
2024-12-29 06:15:29 UTC
2024-12-29 06:15:28 UTC
2024-12-29 06:15:28 UTC
2024-12-29 06:15:28 UTC
2024-12-29 06:15:28 UTC
2024-12-29 06:15:28 UTC
2024-12-29 06:15:27 UTC
2024-12-29 06:15:24 UTC